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Long-term survival rates satisfactory for bladder cancer patients treated with robotic surgery

MedicalNewsToday - 2 hours 26 min ago
In the largest multi-institutional study to date, patients diagnosed with bladder cancer and treated with robot-assisted surgery experienced similar results to those who underwent a traditional...
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The cumulated stone diameter: a limited tool for stone burden estimation

Urology (Gold Journal) In Press - Mon, 06/29/2015 - 00:00
To compare the performance of the main methods used to estimate stone burden in order to improve and standardize preoperative evaluation of stone disease.
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Long-term outcomes following Artificial Urinary Sphincter placement: an analysis of 1082 cases at Mayo Clinic

Urology (Gold Journal) In Press - Mon, 06/29/2015 - 00:00
To evaluate long-term device outcomes following primary artificial urinary sphincter (AUS) implantation.
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Reduced post-vasectomy semen analysis testing with the implementation of special clearance parameters

Urology (Gold Journal) In Press - Mon, 06/29/2015 - 00:00
To determine the applicability of post-vasectomy special clearance parameters (<100,000 non-motile sperm/mL on semen analysis) suggested by the American Urological Association and define the associated cost savings with avoidance of futher testing.
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Artificial Urinary Sphincter Outcomes in the “Fragile Urethra”

Urology (Gold Journal) In Press - Mon, 06/29/2015 - 00:00
To assess artificial urinary sphincter (AUS) outcomes in challenging post-prostatectomy patients with a “fragile urethra” at risk for urethral erosion.
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Re: Shear Wave Elastography for Localization of Prostate Cancer Lesions and Assessment of Elasticity Thresholds: Implications for Targeted Biopsies and Active Surveillance Protocols

We read this article with interest. The authors report that shear wave elastography may allow identification of malignant prostate tissue based on differences in elasticity.
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Development of a Standardized Set of Patient-centered Outcomes for Advanced Prostate Cancer: An International Effort for a Unified Approach

Abstract Background

There are no universally monitored outcomes relevant to men with advanced prostate cancer, making it challenging to compare health outcomes between populations.

Objective

We sought to develop a standard set of outcomes relevant to men with advanced prostate cancer to follow during routine clinical care.

Design, setting, and participants

The International Consortium for Health Outcomes Measurement assembled a multidisciplinary working group to develop the set.

Outcome measurements and statistical analysis

We used a modified Delphi method to achieve consensus regarding the outcomes, measures, and case mix factors included.

Results and limitations

The 25 members of the multidisciplinary international working group represented academic and nonacademic centers, registries, and patients. Recognizing the heterogeneity of men with advanced prostate cancer, the group defined the scope as men with all stages of incurable prostate cancer (metastatic and biochemical recurrence ineligible for further curative therapy). We defined outcomes important to all men, such as overall survival, and measures specific to subgroups, such as time to metastasis. Measures gathered from clinical data include measures of disease control. We also identified patient-reported outcome measures (PROMs), such as degree of urinary, bowel, and erectile dysfunction, mood symptoms, and pain control.

Conclusions

The international multidisciplinary group identified clinical data and PROMs that serve as a basis for international health outcome comparisons and quality-of-care assessments. The set will be revised annually.

Patient summary

Our international group has recommended a standardized set of patient-centered outcomes to be followed during routine care for all men with advanced prostate cancer.

Take Home Message

We convened as an international group to create a standardized set of patient-centered outcomes to follow for all men with advanced prostate cancer. Implementation across health care systems will allow direct comparison of patient outcomes for quality improvement.

Keywords: Outcome assessment (health care), Patient-centered care, Prostate cancer, Quality indicators, Health care, Palliative care.

Footnotes

a Vanderbilt University Medical Center, Nashville, TN, USA

b International Consortium for Health Outcomes Measurement, Cambridge, MA, USA

c Dutch Institute for Clinical Auditing, Leiden, The Netherlands

d Dana-Farber Cancer Institute, Boston, MA, USA

e University of North Carolina at Chapel Hill, Chapel Hill, NC, USA

f University of Pennsylvania, PA, USA

g Gustave Roussy Cancer Institute, Villejuif, France

h Monash University Eastern Health Clinical School, Melbourne, Australia

i Academic Medical Center Amsterdam, Amsterdam, The Netherlands

j Oncology Centre Antwerp, Antwerp, Belgium

k US TOO Belgium, Antwerp, Belgium

l Monash University, Melbourne, Australia

m University of Toronto, Toronto, Canada

n Duke University Medical Center, Durham, NC, USA

o US TOO International, Des Plaines, IL, USA

p University of Washington, Seattle, WA, USA

q St. Vincent's University Hospital, Dublin, Ireland

r University College Hospitals London, London, UK

s Cancer Action Victoria, Melbourne, Australia

t University Hospital Hamburg-Eppendorf, Hamburg, Germany

u Cliniques Universitaires Saint Luc, Université Catholique de Louvain, Brussels, Belgium

v Canisius Wilhelmina Hospital, Nijmegen, The Netherlands

w Leiden University Medical Center, Leiden, The Netherlands

x VA Tennessee Valley Geriatric Research, Education, and Clinical Center (GRECC), Nashville, TN, USA

Corresponding author. Division of Hematology/Oncology, Vanderbilt University Medical Center, 2220 Pierce Avenue, 777 Preston Research Building, Nashville, TN 37232, USA. Tel. +1 615 3224967; Fax: +1 615 3437602.

These authors contributed equally to this work.

Article information

PII: S0302-2838(15)00510-2
DOI: 10.1016/j.eururo.2015.06.007
© 2015 European Association of Urology, Published by Elsevier B.V.

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Clinically insignificant residual fragments: Is it an appropriate term in children?

Urology (Gold Journal) In Press - Sat, 06/27/2015 - 00:00
To assess outcome of clinically insignificant residual fragments (CIRFs) after shock wave lithotripsy (SWL) and percutaneous nephrolithotomy (PNL) in children
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Characteristics of the Peritumoral Pseudocapsule Vary Predictably with Histologic Subtype of T1 Renal Neoplasms

Urology (Gold Journal) In Press - Sat, 06/27/2015 - 00:00
To determine characteristics of the peritumoral pseudocapsule (PC) between renal tumor subtypes.
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Collagenase Clostridium Histolyticum (Xiaflex) for the Treatment of Urethral Stricture Disease in a Rat Model of Urethral Fibrosis

Urology (Gold Journal) In Press - Sat, 06/27/2015 - 00:00
To evaluate the treatment effect of collagenase clostridium histolyticum (CCH) in a rat model of urethral fibrosis.
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Sarcomatoid Carcinoma of the Prostate: Retrospective Review of a Case Series from Johns Hopkins Hospital

Urology (Gold Journal) In Press - Sat, 06/27/2015 - 00:00
To identify survival differences in patients with sarcomatoid prostate cancer based on initial staging and treatment regimens.
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En-bloc technique with anteroposterior dissection holmium laser enucleation of the prostate allows a short operative time and acceptable outcomes

Urology (Gold Journal) In Press - Sat, 06/27/2015 - 00:00
To simplify anteroposterior dissection holmium laser enucleation of the prostate by combining it with a novel en-bloc enucleation technique that omits median lobe enucleation and removes the adenoma en-bloc in benign prostatic hyperplasia patients.
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Holmium Laser Enucleation of the Prostate: Simulation Based Training Curriculum and Validation

Urology (Gold Journal) In Press - Sat, 06/27/2015 - 00:00
To evaluate the face, content, and construct validity of a novel virtual reality simulator for holmium laser enucleation of the prostate (HoLEP) and also assess its feasibility and acceptability as a training model.
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Study highlights 'important safety issue' with widely used MRI contrast agents

MedicalNewsToday - Fri, 06/26/2015 - 08:00
New results in animals highlight a major safety concern regarding a class of magnetic resonance imaging (MRI) contrast agents used in millions of patients each year, according to a paper published...
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A person's diet, acidity of urine may affect susceptibility to UTIs

MedicalNewsToday - Fri, 06/26/2015 - 08:00
The acidity of urine -- as well as the presence of small molecules related to diet -- may influence how well bacteria can grow in the urinary tract, a new study shows.
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New drug delivery system may open up treatments for polycystic kidney disease

MedicalNewsToday - Fri, 06/26/2015 - 05:00
A new method that allows antibodies to penetrate cyst walls may open the door for already approved drugs to target the growth factors that drive polycystic kidney disease.
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Tapping into electronic health records to improve care for patients with chronic kidney disease

MedicalNewsToday - Fri, 06/26/2015 - 03:00
Experts offer guidance on necessary changes related to storing and accessing informationExperts have identified strategies for using electronic health records to improve care for patients with...
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