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Patients who achieve CR after TMT for MIBC remain at risk for intravesical recurrence, which usually requires salvage RC if they have MIBC or high grade pT1 NMIBC. However, with vigilant surveillance regimens these recurrences can be detected before progression to MIBC, and options for management can be discussed in a multidisciplinary setting. Clinicians will need to make management decisions based on clinicopathological factors and overall patient health while trying to minimize treatment morbidity and maximize quality of life.
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Re: Best Practice Policy Statement on Urodynamic Antibiotic Prophylaxis in the Non-Index Patient

A. P. Cameron, L. Campeau, B. M. Brucker, J. Q. Clemens, G. T. Bales, M. E. Albo and M. J. Kennelly
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Re: Perioperative Complications of Conduit Urinary Diversion with Concomitant Cystectomy for Benign Indications: A Population-Based Analysis

E. T. Brown, D. Osborn, S. Mock, S. Ni, A. J. Graves, L. Milam, D. Milam, M. R. Kaufman, R. R. Dmochowski and W. S. Reynolds
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Editorial Comment

Accurate grading and staging are essential to ensure that men with prostate cancer are risk stratified correctly and thereby treated appropriately. In particular, high grade cancers are aggressively treated with surgery, high dose radiation therapy and years of androgen deprivation.1 These treatments are fortunately associated with higher cure rates but they may unfortunately negatively impact quality of life.
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Dusting versus basketing during ureteroscopy – Which technique is more efficacious? A prospective multi-center trial from the EDGE Research Consortium

There is scant evidence in the literature to support dusting stones vs active basket extraction during ureteroscopy for kidney stones. We sought to prospectively evaluate and follow patients to determine which modality produced a higher stone free rate with the least complications.
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The Effect of Nerve Sparing Status On Sexual and Urinary Function: 3−Year Results from the CEASAR Study

Nerve sparing (NS) contributes to recovery of sexual and urinary function after radical prostatectomy (RP) but may be ineffective in some patients or risk positive surgical margin. We evaluated sexual and urinary function outcomes in prostate cancer (PCa) patients treated with RP, according to degree of NS.
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Reply by Authors

We fully agree that the relatively small sample size and the inherent lack of statistical power are major limitations of our findings. Also, the small proportion of wheelchair bound patients as well as patients who performed CIC make it difficult to draw any conclusions regarding these important subpopulations.
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Editorial Comment

The authors present a retrospective, multicenter analysis of bladder neck and bulbar AUS cuff placement in patients with spina bifida who were most commonly not wheelchair bound. Limited data on this patient population increase the relevance of this study.
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Long-term Developmental Adversity and Complex Anomalies

Urology (Gold Journal) In Press - Thu, 12/14/2017 - 00:00
Child development is often divided into normal development and developmental psychopathology. Recently, this latter division has burgeoned because of our increasing awareness of the harsh realities of adverse early events (AEEs) on child development. However, as a field of study child development suffers from at least 2 maladies: (1) developmentalists tend to be shortsighted, seeing child development as an independent field; (2) studies of developmental psychopathology focus almost entirely on external AEEs—that is, child abuse, trauma, or parenting failures.
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Differences in Survival by Receipt of Lymph Node Dissection in Patients with Invasive Penile cancer: Results from the National Cancer Database

Inguinal lymphadenectomy (I-LND) remains underutilized in patients with invasive penile cancer. Using a large national cancer registry, we assessed temporal trends in I-LND utilization and evaluated the impact of I-LND on the survival in patients in whom I-LND is an absolute indication per NCCN guidelines (T1b-4 N0/x-1).
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Re: Penile Neurovascular Structure Revisited: Immunohistochemical Studies with Three-Dimensional Reconstruction

G. N. Yin, S. H. Park, M. J. Choi, A. Limanjaya, K. Ghatak, N. N. Minh, J. Ock, K. M. Song, J. K. Ryu and J. K. Suh
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Re: Delayed Ejaculation and Associated Complaints: Relationship to Ejaculation Times and Serum Testosterone Levels

A. Morgentaler, P. Polzer, S. Althof, A. Bolyakov, C. Donatucci, X. Ni, A. B. Patel and S. Basaria
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Re: Sexual Dysfunction among Diabetics and Its Impact on the SQoL of Their Partners

W. K. B. A. Owiredu, H. Alidu, N. Amidu, C. Obirikorang, C. K. Gyasi-Sarpong, A. T. Bawah, P. P. M. Dapare and A. T. Luuse
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Re: Chemoradiotherapy in Octogenarians as Primary Treatment for Muscle-Invasive Bladder Cancer

V. A. McPherson, G. Rodrigues, G. Bauman, E. Winquist, J. Chin, J. Izawa, K. Potvin, S. Ernst, V. Venkatesan, T. Sexton, B. Ahmad and N. Power
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Re: Second-Line Chemotherapy in Older Patients with Metastatic Urothelial Carcinoma: Pooled Analysis of 10 Second-Line Studies

S. Salah, J. L. Lee, A. Rozzi, H. Kitamura, K. Matsumoto, D. J. Vis, S. Srinivas, R. Morales-Barrera, J. Carles, D. Al-Rimawi, S. Lee, K. H. Kim, K. Izumi and J. Lewin
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