Urology News Feeds

Diabetic bladder dysfunction: A review

Urology (Gold Journal) In Press - Sat, 10/20/2018 - 00:00
Diabetic bladder dysfunction (DBD) affects almost half of all diabetic patients, making it one of the most common complications of diabetes mellitus. The clinical presentation of DBD can be varied and may be extremely bothersome to patients, negatively impacting their quality of life. Despite this, it remains under-studied and under-represented in the medical literature. This review summarizes the current literature on pathophysiology, clinical presentation, urodynamic findings, evaluation and management.
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REPLY TO LETTER-TO-THE-EDITOR: "CONCERNS ABOUT THE USE OF A FREE GRAFT DURING YORK-MASON INTERVENTION"

Urology (Gold Journal) In Press - Wed, 10/17/2018 - 00:00
While we recognize the thoughtful nature of this critique regarding the use of interposing fat grafts during the Modified York Mason procedure, we disagree with the concept that aberrant functionality or healing results. On the contrary, urinary and fecal streams are individually repaired to completion—the fat graft then is placed between the water-tight suture lines as a finalizing barrier. We reject the notion that interposing fat in this manner creates anatomic distortion of any physiologic significance.
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Estimating Minimally Important Differences for the Bladder Cancer Index Using Distribution- and Anchor-Based Approaches

The Bladder Cancer Index is a validated condition-specific health questionnaire assessing urinary, bowel and sexual function and quality of life among bladder cancer patients. We aimed to establish minimally important difference score thresholds that signal clinical importance.
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Can you take too much magnesium?

MedicalNewsToday - Tue, 10/16/2018 - 14:00
Magnesium is essential for health, but taking too much can cause problems, including digestive issues, lethargy, and an irregular heartbeat. In rare cases, an overdose can be fatal. Learn more here.
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Concurrent radiotherapy and panitumumab after lymph node dissection and induction chemotherapy for invasive bladder cancer

In this prospective study we evaluated safety and efficacy of concurrent radiotherapy and panitumumab following neoadjuvant/induction chemotherapy (ICT) and pelvic lymph node dissection (PLND) as a bladder preserving therapy for invasive bladder cancer (BC).
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Robotic-assisted radical cystectomy vs open radical cystectomy: systematic review and meta-analysis

To perform an updated systematic review and meta-analysis evaluating patient important outcomes for patients undergoing robot-assisted radical cystectomy (RARC) and open radical cystectomy (ORC).
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The Impact of Agent Orange Exposure on Prostate Cancer Outcomes

This study explores the effect of Agent Orange (AO) exposure on prostate cancer (PCa) survival in Veterans Affairs (VA) patients receiving androgen deprivation therapy (ADT) for advanced PCa.
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Career Expectations and Preferences of Urology Residency Applicants

Urology (Gold Journal) In Press - Thu, 10/11/2018 - 00:00
To survey the characteristics, career goals, and practice preferences of current urology applicants.
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Psychiatric Diagnoses and Other Factors Associated with Emergency Department Return within 30 Days of Ureteroscopy

Emergency department(ED) visits after ureteroscopy(URS) are costly and inconvenient. To better understand those at risk, we aim to identify patient demographic, medical and surgical factors associated with 30-day ED presentation following URS for urolithiasis with particular attention paid to those with a history of a psychiatric diagnosis(PD).
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Intravesical gentamicin treatment for recurrent urinary tract infections caused by multidrug-resistant bacteria

Antimicrobial resistance leads to complications in the management of recurrent urinary tract infections (rUTIs). In some rUTI patients with limited treatment options, intravenous therapy with reserve antibiotics is often required. In this study we aimed to assess the effectiveness, safety, and feasibility of prophylactic treatment with intravesical gentamicin in patients with refractory rUTI caused by multidrug-resistant (MDR) microorganisms.
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Effect of Lesion Location on Prostate Cancer Detection Rate with Magnetic Resonance Imaging Targeted Biopsy in African Americans

The updated Prostate Imaging Reporting and Data System version 2 (PI-RADSTM v2) defines different grading parameters for lesions located in the peripheral zone (PZ) versus the transitional zone (TZ) and has contributed to the implementation of magnetic resonance imaging targeted biopsy (MRI-TB). This study evaluated the efficacy of MRI-TB between African American patients with additional consideration for lesion location on MRI.
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Post-Surgical Imaging Patterns in Pediatric Nephrolithiasis: Opportunities for Improvement

Imaging following surgical intervention for nephrolithiasis is important to define surgical success as well as to ensure no silent obstruction. We assessed nationwide post-surgical imaging patterns in children undergoing ureteroscopy (URS) and shock wave lithotripsy (SWL).
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Hypofractionated Radiation Therapy for Localized Prostate Cancer: An ASTRO, ASCO, and AUA Evidence-Based Guideline

The aim of this guideline is to present recommendations regarding moderately hypofractionated (240-340 cGy per fraction) and ultrahypofractionated (500 cGy or more per fraction) radiation therapy for localized prostate cancer.
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MicroRNA expression profiles in upper tract urothelial carcinoma differentiate tumor grade, stage and survival: implications for clinical decision-making

Urology (Gold Journal) In Press - Wed, 10/10/2018 - 00:00
To evaluate microRNA biomarkers for upper tract urothelial carcinoma (UTUC) to improve risk stratification.
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Hypoglycemia in Renal Cell Carcinoma: A Rare Paraneoplastic Syndrome

Urology (Gold Journal) In Press - Tue, 10/09/2018 - 00:00
A 65-year-old male adult foster care patient presented to the emergency room with altered mental status and respiratory depression which required intubation. The patient was also found to be hypoglycemic and hypertensive. He was admitted to the medical intensive care unit where a chronic type B aortic dissection and an exophytic superior pole right renal mass measuring 4.5 × 5.5 cm were discovered on CT scan (Figure 1). He continued experiencing recurrent episodes of hypoglycemia during his admission and was placed on double portion meals and intravenous glucose with dextrose 10% (D10) in water.
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SEMEN PARAMETERS AMONGST TRANSGENDER WOMEN WITH A HISTORY OF HORMONAL TREATMENT

Urology (Gold Journal) In Press - Tue, 10/09/2018 - 00:00
To report on the semen quality parameters in transgender women who pursued semen cryopreservation either in the presence or absence of gender affirming hormonal medication.
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Cryobiopsy in the upper urinary tract: Preclinical evaluation of a novel device

Urology (Gold Journal) In Press - Tue, 10/09/2018 - 00:00
To develop a novel device for cryobiopsy of the upper urinary tract (UUT) and to evaluate its feasibility in a standardized preclinical setting.
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Outpatient Surgical Management for Acquired Buried Penis

Urology (Gold Journal) In Press - Tue, 10/09/2018 - 00:00
To demonstrate the safety and feasibility of outpatient surgical management for patients with acquired buried penis.
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Clinical proof-of-concept of a novel platform utilizing biopsy-derived live single cells, phenotypic biomarkers, and machine learning toward a precision risk stratification test for Prostate Cancer Grade Groups 1 and 2 (Gleason 3+3 and 3+4)

Urology (Gold Journal) In Press - Tue, 10/09/2018 - 00:00
To examine the ability of a novel live primary-cell phenotypic (LPCP) test to predict post-surgical adverse pathology (AP) features and risk stratify patients based on surgical adverse pathology features in a blinded study utilizing radical prostatectomy (RP) surgical specimens.
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