Urology News Feeds
Nocturnal polyuria (NP), the most common etiology of nocturia, is a bothersome condition characterized by overproduction of urine at night.1,2 NP may result from abnormalities in the normal circadian variation in endogenous arginine vasopressin (AVP) secretion,3 and it can also be associated with various medical conditions, including congestive heart failure, diabetes mellitus, obstructive sleep apnea, peripheral edema, excessive night-time fluid intake, as well as “normal” aging.4 There is a strong need to manage this burdensome condition by identifying the causative factors and associated comorbidities.
Superior Mesenteric Artery Syndrome (SMAS) is a rare condition of external duodenal compression in the angle between the superior mesenteric artery and aorta. We report a case of SMAS following augmentation cystoplasty in a young patient.
Sepsis following transrectal prostate biopsy occurs in 2-5% of cases and the risk is increasing. We performed a comprehensive literature search for the cost of post-prostate biopsy sepsis to define the potential cost savings of reducing infectious complications. Reporting of cost is varied and presents a challenge to interpretation. Length of hospitalization ranged from 1.1-14 days and the percent admitted to an ICU ranged from 1.1-25%. The estimated cost of sepsis post-prostate biopsy, adjusted for inflation, ranged from $8,672-$19,100.
A retrospective cohort study on surgical outcomes of penile prosthesis implantation surgery in transgender men after phalloplasty.
To assess surgical outcomes of penile prosthesis implantation in transgender men who underwent phalloplasty.
Presenting Complications to a Reconstructive Urologist after Masculinizing Genital Reconstructive Surgery
To evaluate the presenting complications of patients to reconstructive urologists after masculinizing gender affirming genital reconstructive surgery (GRS) performed elsewhere.
A 70 year old female was referred to the outpatient department of our institute with complaints of fatigue, bilateral flank pain and loss of appetite for the past 1 month. She also complained of shortness of breath and decreased urine output for the past 7 days. Previous surgical and medical history of the patient was unremarkable. She was thin built and undernourished with a BMI of 17kg/m2. On examination, the patient had bilateral pedal edema and fine crackles on respiratory examination. The cardiovascular examination of the patient was essentially normal.
Trends In Stress Urinary Incontinence Surgery at a Tertiary Center: Midurethral Sling Use Following The AUGS/SUFU Position Statement
To investigate trends in stress urinary incontinence (SUI) surgery before and after the 2011 FDA notification and the 2014 AUGS/SUFU position statement.
Impact of urology resident involvement on intraoperative, long-term oncologic and functional outcomes of robotic assisted laparoscopic radical prostatectomy
To evaluate the impact of resident involvement in robot assisted laparascopic prostatectomy (RALP) on oncologic, functional, and intraoperative outcomes, both short and long term.
A 69-year-old man with a history of rheumatoid arthritis and pulmonary fibrosis presented with an incidentally discovered 11.5 cm left renal mass with a level 3 inferior vena cava (IVC) tumor thrombus, including involvement of the left adrenal and lumbar veins. The thrombus was highly vascularized as shown in Figure 1A-C. Preoperative evaluation was negative for metastatic disease and the serum creatinine (SCr) level was 1.55 mg/dL, correlating with an estimated glomerular filtration rate (eGFR) of 46 mL/min/1.73m2.
We reviewed the literature for the biologic, prognostic, and predictive significance of circulating prostate cancer tumor cells (CTCs), and circulating tumor DNA (ctDNA) in the blood of metastatic castration resistant prostate cancer patients (mCRPC). CTCs demonstrate robust prognostic value independent of PSA in predicting overall survival. The CTC androgen receptor variant receptor 7 (AR-V7) phenotype predicts resistance to androgen receptor synthesis inhibitors and sensitivity to taxane based chemotherapy in mCRPC patients who are candidates for second line therapy.
Male-to-Female Gender Reassignment Surgery: An Institutional Analysis of Outcomes, Short-Term Complications, and Risk Factors for 240 Patients Undergoing Penile-Inversion Vaginoplasty
To report outcomes, complications, and risk factors of a population cohort undergoing Male-to-Female (MtF) gender affirmation surgery via penile-inversion vaginoplasty by a single surgeon at a large academic institution. As gender dysphoria awareness increases among the medical community, so does the population of patients seeking gender-affirmation surgery.
Combination of LIM-kinase 2 and Jun amino-terminal kinase inhibitors improves erectile function in a rat model of cavernous nerve injury
To determine if combined administration of LIMK2 and JNK inhibitors in a rat model of ED induced by cavernosal nerve (CN) injury could restore erectile function by suppressing both cavernosal apoptosis and fibrosis via rectification of molecular pathways related to the structural alterations.
Shorter hospital stay and fewer hospitalisations in patients with visible haematuria on direct oral anticoagulants compared to on vitamin K antagonists
To investigate the influence of type of anticoagulation - direct oral anticoagulants (DOAC) vs. vitamin K antagonists (VKA) – on length of hospital stay (LOS) and hospitalisation rates in patients with visible haematuria, as visible haematuria in anticoagulated patients can be distressing, difficult to control and even life-threatening.
Incidence of port site metastasis in laparoscopic radical nephroureterectomy: Single-institution experience
To address the incidence and potential risk factors of port site metastasis (PSM) in patients who underwent laparoscopic radical nephroureterectomy (RNU) for upper tract urothelial carcinoma (UTUC).
Impact of Neoadjuvant Chemotherapy on Concordance of PD-L1 Staining Fidelity between the Primary Tumor and Lymph Node Metastases in Bladder Cancer
To evaluate programmed death ligand 1 (PD-L1) staining fidelity between the primary tumor and associated lymph node metastases in bladder cancer. To secondarily evaluate whether neoadjuvant chemotherapy (NAC) affects this relationship.
To determine if reported incidence rates of hemorrhagic cystitis after radiation therapy for prostate cancer are accurate, to investigate the effect of different radiation modalities on the development of hemorrhagic cystitis and to assess its morbidity and treatment.
A PROSPECTIVE STUDY TO EVALUATE EFFICACY USING THE NURO™ PERCUTANEOUS TIBIAL NEUROMODULATION SYSTEM IN DRUG-NAÏVE PATIENTS WITH OVERACTIVE BLADDER SYNDROME (OAB)
To evaluate changes from baseline in urgency urinary incontinence (UUI) episodes, urinary frequency (UF) and quality of life through 12 weeks of percutaneous tibial neuromodulation (PTNM) therapy using NURO in drug-naïve OAB subjects.
Survival Benefit Persists with Delayed Initiation of Adjuvant Chemotherapy following Radical Cystectomy for Locally Advanced Bladder Cancer
To determine if delaying the initiation of adjuvant chemotherapy following radical cystectomy for locally advanced bladder cancer worsens overall survival.
Letter-to-the-Editor Reply: "The Impact of 68Ga-PSMA PET/CT and PET/MRI on the Management of Prostate Cancer"
Eric A. Klein, MD Editor in Chief
To determine the prevalence of burnout in urology trainees and examine the influence of personal, programmatic, and institutional factors on burnout rates.