Urology News Feeds
Analysis of Spatial Dose-Volume Relationships and Decline in Sexual Function Following Permanent Brachytherapy for Prostate Cancer
To explore relationships between dose to periprostatic anatomic structures and erectile dysfunction (ED) outcomes in an institutional cohort treated with prostate brachytherapy.
To investigate the role of albuminuria as a clinical marker of early renal disease in children with neurogenic bladder (NGB) in association with commonly used predictors of renal risk.
Focal high-intensity focussed ultrasound partial gland ablation for the treatment of localised prostate cancer: a report of medium-term outcomes from a single-centre in the United Kingdom
To report our intermediate outcomes of the use of focal ablation for treating significant unilateral prostate cancer. This technique was adopted in our centre ten years ago. With improving diagnostic accuracy of index prostate cancer lesions and a low side-effect profile, use of focal HIFU ablation is increasing.
To describe a stepwise management of patients with interstitial cystitis/bladder pain syndrome (IC/BPS) with Hunner's lesions and present single institution long-term outcomes.
The list of unmet clinical needs in prostate cancer is long. Although the problems of overdiagnosis and overtreatment of prostate cancer are increasingly acknowledged by the medical community, the fact remains that this disease is still the second most common cause of cancer-related deaths in men. Nevertheless, significant progress has been made toward characterizing the complex biology of this disease, and advances in imaging techniques that improve the detection of clinically significant cancers have occurred in recent years.
To determine the long-term rate of posterior compartment prolapse (PCP) occurrence after native tissue repair of the anterior compartment with anterior vaginal wall suspension (AVWS) procedure.
To determine if the timing of radical cystectomy for variant histology of urothelial carcinoma has an impact on survival. Variant histology has been associated with aberrant behavior compared to pure urothelial carcinoma, however the timing of surgery for these patients has not been studied.
A 38-year-old Caucasian male was referred to our emergency service complaining of acute pain in the left side of the scrotum. Medical history revealed that the patient felt a sudden sharp scrotal pain that begun 72 hours before admission. It was spreading to the ipsilateral side of the lower abdomen. The intensity of pain was not alleviated over time. There was no history of recent trauma, previous inguinoscrotal surgery nor cryptorchidism. At the presentation, he was febrile up to 38o C. Physical examination revealed the swollen, erythematous left side of the scrotum with painful tumefaction above the testicle (Figure 1).
Tumors discovered antenatally are rare and the prognosis is generally poor. We present a case of a fetal left renal mass, initially discovered via routine prenatal ultrasound. The mother was an otherwise healthy gravida four para one 30-year-old female with two previous miscarriages, reportedly secondary to septate uterus. Further imaging and subsequent genetic testing was consistent with an antenatal Wilms’ tumor with a mutation in the NPHP1 gene. The newborn received chemotherapy and had no evidence of reccurrence at three months follow-up.
Acute Presentation of Previously Unrecognized Congenital UPJ Obstruction 5 Weeks after Radical Retropubic Prostatectomy
A 61-year-old Caucasian male presented to the emergency department (ED) with a three-day history of increasing fatigue and recent onset of fever and shaking chills. He did not have any localizing signs or symptoms. Importantly, the patient had undergone open radical retropubic prostatectomy (RRP) five weeks prior for pT3aNxMxR0 Gleason 3+4=7 prostate cancer identified on biopsy for elevation in serum prostate specific antigen (5.38 ng/ml). This patient had a preoperative right-sided nodule (consistent with cT2b disease) and Gleason 3+4=7 in 8 of 12 cores.
Association between Tumor Multifocality on Multi-parametric MRI and Detection of Clinically-Significant Prostate Cancer in Lesions with Prostate Imaging Reporting and Data System (PI-RADS) Score 4
To investigate whether presence of multifocality on multi-parametric magnetic resonance imaging (mpMRI) would increase the likelihood of detecting clinically-significant prostate cancer (csPCa) in a PI-RADS 4 lesion.
Diagnostic performance of prostate multiparametric magnetic resonance imaging in African-American men
To compare test performance of multiparametric magnetic resonance imaging (mpMRI) for detection of prostate cancer (PCa) in African-American men (AAM) and white men (WM) using the Prostate Imaging Reporting and Data System (PIRADS) in unmatched groups as well as a cohort matched for clinical factors.
To present the surgical approach to a cystic renal mass suspicious for malignancy in a 22 month old female.
Robot-assisted radical prostatectomy due to a primary carcinoid prostatic tumour in a three-year-old child: a case report
We present an extremely rare case of a 3-year-old child with a primary carcinoid tumour of the prostate. A 3-year-old boy presented with failure to thrive, constipation, recurrent respiratory tract infections and pain in the genital area. His karyotype was normal and cystic fibrosis and coeliac disease were excluded prior to further investigation. An abdominopelvic CT scan revealed a prostatic mass. Transrectal ultrasound-guided prostate biopsy was therefore performed and pathological examination revealed a carcinoid tumour.
To evaluate the safety, efficacy, and oncologic control of percutaneous image-guided cryoablation in the treatment of completely endophytic renal masses. Percutaneous image-guided cryoablation is a minimally invasive and effective treatment for small renal masses. Image-guided cryoablation is an attractive treatment for completely endophytic tumors given the challenge in visualization of such lesions during surgical extirpation.
The minimum clinically important difference of the International Consultation on Incontinence Questionnaires (ICIQ-UI SF and ICIQ-LUTSqol)
To estimate the minimum clinically important difference (MCID) of the International Consultation on Incontinence Questionnaire-Urinary Incontinence Short Form (ICIQ-UI SF) and the International Consultation on Incontinence Questionnaire-Lower Urinary Tract Symptoms Quality of Life (ICIQ-LUTSqol) using both anchor-based and distribution-based methods for women with stress urinary incontinence undergoing non-surgical treatment.
The Management and Efficacy of Surgical Techniques used for Erosive Mesh in the Urethra and Bladder: A Systematic Review
This study reports the re-operation and symptom resolution rates of different techniques used in surgical excision of genitourinary mesh erosions. A comprehensive systematic review was completed after searching electronic databases for studies involving outcomes of mesh erosion in humans that were managed surgically using a transvaginal, cystoscopic, or abdominal approach. Surgical outcomes were reported in percentages, ranges, and simple pooling to generate trends in management techniques. There were 177 cases that met our inclusion criteria.
To determine the importance of the duration of in-hospital management of patients with testicular torsion for testes survival. The time from onset of symptoms until surgery is a well-known factor determining testicular survival but there is no data regarding the contribution of in-hospital management duration to testicular survival. Unlike the time from onset of symptoms until seeking medical attention, the time from registration to the ED to the time of detorsion - "Door To Detorsion time" (DTD) is dependent on medical providers and should be minimized.
Fetal rhabdomyomatous nephroblastoma (FRN) is a rare variant of Wilms tumor with distinct morphologic features and biologic behavior compared to conventional nephroblastoma. It mainly occurs in patients under 4 years. In adults, extremely rare cases of nephroblastoma were reported. Among these cases, none has interested a FRN. We report an exceptional case of a 31-year-old woman diagnosed with FRN discovered incidentally, to illustrate clinical and histopathological characteristics of this entity.
To present the surgical approach to a multifocal Wilms tumor found on screening ultrasound in an asymptomatic 2-year-old female.