Urology News Feeds
An Enhancing Renal Mass in Metastatic Prostate Cancer
A 59-year-old male with a history of metastatic prostate cancer (mPCa) was seen in clinic. He had been diagnosed four years prior and received docetaxel and hormonal therapy. Response to systemic treatment was excellent and he underwent radical prostatectomy with lymph node dissection as part of a clinical trial. Final pathology was ypT3bN1 with left seminal vesicle invasion and negative margins. His PSA was undetectable post-operatively and he received adjuvant pelvic radiation. Cross-sectional imaging after radiation was negative for residual metastatic disease.
Lycopene in prevention of infertility after testicular surgery
Tuncer et al1 reported a case of testicular replantation following wrong-site surgery in a young man with testicular cancer. They have successfully treated the patient, but they had concerns about poor recovery of sperms after surgery due to ischemia time resulting in oxidative stress and inflammation. In testicular amputation cases, preservation of the fertility poses a challenge. However, it is now possible to cryopreserve functional sperm from amputated testis in a post-pubertal patient. In addition, nutritional interventions may help protect the sperms from oxidative damage during their development by preventing oxidative stress and inflammation2-4.
Robotic-Assisted Augmented Roof Ureteroplasty with Appendiceal Onlay Flap
Mid-to-proximal ureteral strictures pose a surgical challenge that historically required ileal ureter substitution, downward nephropexy, or renal autotransplantation. Ureteral reconstruction techniques involving buccal mucosa or appendix have gained traction with success rates approaching 90%.
What's in a p-value? A fragility analysis of RCTs in the AUA guidelines for benign prostatic hyperplasia
To use the Fragility Index (FI) and Fragility Quotient (FQ) to assess the strength of statistically significant findings for randomized controlled trials (RCTs) cited in the American Urological Association (AUA) guidelines for benign prostatic hyperplasia.
The Impact of the Virtual Interview on Candidate Experience and Outcomes: Society of Academic Urologists National Survey of Interns Who Participated in the 2020-2021 Urology Match
To examine retrospective experiences with the virtual interview (VI) process among post-graduate year 1 (PGY1) urology residents who participated in the 2020-2021 American Urologic Association (AUA) Match cycle.
Pelvic Exenteration and Abdomino-Perineal Resection in a Transgender Female with Squamous Cell Carcinoma of Unknown Origin
A 56-year-old adult presented 25 years after penile inversion genital gender affirming vaginoplasty with complaints of abdominal pain and purulent neovaginal discharge. Physical exam revealed a patent neovagina with diffuse tumor involving the cul-de-sac and rectum. She was sexually active. A neo-urethral meatus was patent and functional without involvement. Colonoscopy revealed an obstructing rectal mass. Cross sectional imaging revealed a 10-cm mass in the pelvis, extending from the anterior rectal wall to the posterior bladder wall.
INTERNATIONAL SURVEY ON URODYNAMIC INVESTIGATIONS IN WOMEN UNDERGOING STRESS URINARY INCONTINENCE SURGERY
To evaluate the role of invasive urodynamics (UD) in women candidates for stress urinary incontinence (SUI) surgery.
Utilizing a Questionnaire to Implement a Risk-Based Antibiotic Prophylaxis Protocol for Transrectal Prostate Biopsy
To develop and evaluate a risk-based antibiotic prophylaxis protocol for patients undergoing transrectal prostate biopsy.
Penile and foreskin stretching practices through time and culture
Currently, the medical literature suggests there is objective benefit to penile stretching and traction therapy in Peyronie's disease, in post-prostatectomy patients to prevent penile shortening, in erectile dysfunction prior to placement of an inflatable prosthesis, and for men concerned about penile length.1 While this evidence in the literature regarding the medical benefit of penile traction therapy is quite recent, penile stretching practices are not new from a historical perspective.
Current practice patterns in the surgical management of benign prostatic hyperplasia
To use American Board of Urology (ABU) case log data to elucidate practice patterns for BPH surgery. Several modalities have been introduced in recent decades have caused significant practice variation.
Incremental Treatment Response by Cycle With Collagenase Clostridium Histolyticum for Peyronie's Disease: a Pooled Analysis of Two Phase 3 Trials
To evaluate cumulative and incremental changes in penile curvature after each treatment cycle of collagenase clostridium histolyticum (CCH) in men with Peyronie's disease (PD).
Renal Location Within the Retroperitoneum in Various Body Positions Using Magnetic Resonance Imaging: Implications for Percutaneous Nephrostolithotomy
To assess the difference in cranio-caudal renal position in both the supine and prone position, as well as the effect of arm position on renal location, using magnetic resonance imaging in subjects with BMI <30.
Removal of a hard plastic bottleneck causing penile strangulation with holmium laser
A 44-year-old male presented to our emergency department with a chief complaint of a hard plastic bottleneck strangulating around the base of his penis for 3 hours. The patient inserted his penis into a bath lotion bottle for masturbation, of which the bottleneck was approximately 1.8 centimeters in diameter. Due to penis swelling, congestion and pain, the patient found that the penis could not be pulled out after 2 hours. He tried to remove it completely by himself but failed. As the patient was concerned about penile necrosis, he sought emergency care at our hospital.
Whole Exome Sequencing Identifies a Rare CFTR Mutation in Brothers With Anomalies of the Vas Deferens: a case study
Congenital bilateral absence of the vas deferens (CBAVD) occurs in almost all men with Cystic Fibrosis. Prevailing theories on this pathophysiology relate to pathogenic mutations in the Cystic Fibrosis Transmembrane Regulator (CFTR) gene leading to agenesis or obliteration of vas deferens in utero. In this study, we present a case of two brothers with congenital anomalies of the vas deferens who were found to have carry a rare, heterozygous CFTR variant p.r347h without pulmonary or gastrointestinal signs or symptoms of CF.
Within State Variability of Antimicrobial Susceptibility: Missouri as an Archetype to Assess Guidelines for Antimicrobial Prophylaxis for Transurethral Procedures
To evaluate variability among hospitals in susceptibility of common uropathogens to antimicrobial agents frequently used in transurethral procedures in order to examine whether state-based guidelines might be more appropriate than national prophylactic guidelines.
Staphylococcus epidermidis as a uropathogen in children
Historically, Staphylococcus epidermidis has been considered a contaminant when grown on urine cultures. However, a growing body of literature suggests that S. epidermidis can cause urinary tract infections (UTIs) in children with anatomic variants or a history of instrumentation. In this case report, we describe a previously healthy child who presented with symptoms of UTI and urine cultures grew this uropathogen. The patient was screened for anatomic abnormalities and none were found; nonetheless, appropriate treatment should be initiated even if no underlying pathology is found.
Association between pre-surgical weight status and urinary and sexual function in prostate cancer patients treated by radical prostatectomy: a prospective cohort study
To prospectively examine the influence of weight status on urinary and sexual function in clinically localized prostate cancer patients treated by radical prostatectomy (RP).
Unexpected pediatric uretero-inguinal hernia: case-report and literature review
Uretero-inguinal hernia (UIH) is a rare condition in children. We present our experience with an unexpected UIH in a male infant with associated anomalies and a literature review of pediatric cases.A full-term male newborn was referred to our hospital for microcolon and right hydroureteronephrosis. Voiding cystourethrography showed grade-IV right vesicoureteral reflux and a dilated, convoluted, ureter protruding in the right inguinal canal, suggesting a right UIH, which was uneventfully repaired at two months of life.
Short- and intermediate-term outcome of robot-assisted inverted YV-plasty for recurrent bladder neck stenosis - a single centre study
To report the technique and preliminary results for extraperitoneal robot-assisted laparoscopic YV-plasty (RAYV) for refractory bladder neck stenosis (BNS) and vesicourethral anastomosis stenosis (VUAS).
Gleason grade group concordance between systematic template combining magnetic resonance imaging fusion targeted biopsy and radical prostatectomy specimens: A comparison of transperineal and transrectal approaches
To evaluate the Gleason grade (GG) discrepancy between biopsy (Bx) techniques (transperineal (TP) /transrectal (TR) approaches or multiparametric magnetic resonance imaging (mpMRI) targeted biopsy (TBx) / standard template biopsies (SBx)) and prostatectomy (RP) specimens.