Urology News Feeds
Rainer Engel, The Gatekeeper of Urologic History
Rainer Engel (1933-2018) was a dedicated urologist for over 20 years in the Baltimore, Maryland area. He then spent the next 23 years as curator of the William P Didusch museum and gave the stories and tools and events that created the urology-of-today life. Here we delve into his life and his impact on urology and how we look at urologic history.
Highlighting Gender Differences in RLS: Analysis of Gender in Robotic and Laparoscopic Surgical Volume in Urology versus Other Subspecialties
To evaluate the involvement of women surgeons in RLS over time and across fields. While women are an increasing proportion of the urological workforce, the overall percentage of women urologists remains low. As robotic/laparoscopic surgery (RLS) has become first-line for many surgical problems, we hypothesized that women in urology may have lower participation than other specialties.
Bilateral Cavernosal Artery Ligation to Treat Ischemic Priapism following Inflatable Penile Prosthesis Implantation
To describe the first known case of recurrent acute priapism after penile prosthesis implantation.
NORMAL GLANULAR AND MEATAL MEASUREMENTS IN BOYS AND MEN
To determine the normal vertical urethral meatus length (ML), maximum glanular width (MGW), the glanular seam length (between the lowest edge of urethral meatus and the glans closure line corona) (GSL) and GSL/ML ratio in all age groups.
Compensated hypospermatogenesis: elevated follicle-stimulating hormone predicts decline in semen parameters among men with normal index semen analysis
To determine whether men with elevated follicle-stimulating hormone (FSH) and normal semen analysis (SA) are more likely to experience a decline in semen parameters over time compared to men with normal FSH.
Clinical Challenge: Patient with Genital Lymphedema, Pain, and Rash
A 47-year-old man presented to the emergency department (ED) with 3 days of worsening scrotal pain, genital edema, erythema and yellow penile discharge, after completing 2 weeks of doxycycline. He was in an open marriage with a male partner and denied new sexual partners. In the ED he was afebrile and normotensive without tachycardia. His physical exam revealed tender genital lymphedema without crepitus or fluctuance (Figure 1A, 1B). White blood cell count (WBC) was 8.8 × 109/L, Lactate 1.9 mmol/L, and Creatinine 1.22 mg/dL.
Variation in Provider Practice Patterns and the Perceived Need for a Shared Decision-making Tool for Neurogenic Lower Urinary Tract Dysfunction
To evaluate NLUTD care providers’ current practice patterns, their perceived need for a shared decision-making tool for NLUTD management.
Prosteria - National Trends and Outcomes of More Frequent than Guideline Recommended Prostate Specific Antigen Screening
To characterize national trends in and associated outcomes of more often than annual PSA screening, which we term “prosteria”.
Patient-Reported Financial Toxicity Associated with Management of Nephrolithiasis
To characterize stone-related financial burden among adults with nephrolithiasis through validated questionnaires for financial toxicity.
3D CT Urethrography with Cinematic Rendering (3DUG): A New Modality for Evaluation of Complex Urethral Anatomy and Assessment of the Postoperative Phalloplasty Urethra
To develop an imaging modality for the postoperative phalloplasty urethra. Despite high urologic complication rates after masculinizing genital surgery, existing methods for post-surgical evaluation after phalloplasty have drawbacks. Fluoroscopic studies like the retrograde urethrogram have limitations like user-dependence and meticulous positioning but also are inadequate for the evaluation of the anatomically distinct post-phalloplasty urethra. We developed a novel protocol utilizing CT urethrography with 3D reconstruction using cinematic rendering (3DUG) for neo-urethral imaging.
Objective Quantification of Detrusor Overactivity using Spectral Measures of Cystometry Data
To develop scalable objective methods for differentiating patients with and without detrusor overactivity (DO) using quantitative Fast Fourier Transform (FFT)-based measures and routinely captured cystometry data
The Utility of Radiologic and Symptomatic Surveillance After Minimally-Invasive Adult Pyeloplasty
To evaluate different types of failure after minimally-invasive pyeloplasty (MIP) when stratified by initial radiologic study and symptoms after ureteral stent removal.
Perceptions of Gender Equity by Urologic Subspecialty
To evaluate how urologists in various subspecialties view the climate for female urologists, comparing perceptions of gender inequity based on characteristics including gender, subspecialty training, faculty status, parental status, and years in practice. Despite growth in female representation in urology, gender inequalities in career opportunities and compensation continue to exist.
Time Matters: Importance of Circadian Rhythms, Disruption, and Chronotherapy in Urologic Malignancies
The human body was evolutionarily programmed to run on cycles, termed circadian rhythms, which integrate human behavior and bodily function with the environment. Disruption to these rhythms via desynchronization have been deemed a probable carcinogen by the WHO. Subsequent research has identified alterations in multiple core clock genes when comparing tumor and benign tissues. This review will discuss core clock genes associated with urogenital malignancies and highlight impactful research regarding circadian biology use in treatment.
Contemporary Systemic Therapies in Urothelial Carcinoma
Prior to the past decade, systemic therapy options for muscle-invasive bladder cancer (MIBC) or locally advanced/metastatic urothelial carcinoma (la/mUC) were dismal for cisplatin-ineligible patients and after progression on chemotherapy. Although the bulk of available evidence for novel systemic therapies exists in the la/mUC setting, emerging data suggests an important role in the neoadjuvant and adjuvant spaces as well. In this narrative review, we examine the application of contemporary systemic therapies to urothelial carcinoma (UC) including immune checkpoint inhibitors (ICIs), antibody-drug conjugates (ADCs), and targeted therapies.
Utility of pre-transplant bladder cycling for patients with a defunctionalized bladder. A randomized controlled trial
To study the necessity of pre-transplant programmed bladder cycling (PBC) in patients with defunctionalized bladder (DB).
Upper Tract Tumor En Bloc Enucleation: A Novel Approach to the Diagnosis and Management of Upper Tract Urothelial Carcinoma
To describe and demonstrate our novel en bloc enucleation technique for the endoscopic diagnosis and treatment of upper tract tumors.
Holistic assessment of quality of life predicts survival in older patients with bladder cancer
To determine if clustering methods can use a holistic assessment of health-related quality-of-life after BC diagnosis to predict survival outcomes independent of clinical characteristics. In the United States, an estimated 81,180 cases of bladder cancer (BC) will be diagnosed in 2022. We aim to help address the knowledge gap concerning the impact of patient functional status on outcomes.
SURGICAL OUTCOMES AT A SINGLE INSTITUTION OF INFRAPUBIC INSERTION OF MALLEABLE PENILE PROSTHESIS IN TRANSMEN
To describe our technique for the infrapubic approach for malleable penile prosthesis (MPP) insertion after phalloplasty in transgender men and review surgical outcomes.
Partial Component Exchange of a Non-infected Inflatable Penile Prosthesis is Associated with a Higher Complication Rate
To describe the infectious and non-infectious complications in men undergoing IPP revision with partial and complete component exchange for mechanical malfunction.