Urology News Feeds
Management of a Prostate Cancer Patient with inherited germline BRCA1 and BRCA2 mutations, a Case Report
The Breast Cancer Gene (BRCA) confers an 8.6-fold higher risk of developing prostate cancer in men ≤ 65 years of age and portends a worse prognosis as compared to noncarriers even in patients with low volume, localized disease. The BRCA2 gene, in particular, imparts a more biologically aggressive form of prostate cancer and a higher prostate cancer specific mortality. From a treatment standpoint, this translates to worse overall clinical outcomes for such patients. The most appropriate screening and management strategy for germline BRCA mutation carriers with prostate cancer is not known.
Revision for Inflatable Penile Prosthesis (IPP) Surgery: A Single-Center Experience and Pictorial Representation
To elucidate factors influencing IPP revision and describe outcomes associated with revision surgery.
To outline the principles and premise, pros and cons of the use of preference signaling (PS) in the Urology Match.
To determine the risk of complications requiring treatment following male circumcision by health-care professionals and to explore the impact of participant characteristics, type of circumcision and study design.
Photoselective Vaporization of the Prostate in the Management of Lower Urinary Tract Symptoms in Prostate Cancer Patients on Active Surveillance
To demonstrate the safety and efficacy of photoselective vaporization of the prostate in alleviating refractory lower urinary tract symptoms in prostate cancer patients who are managed with active surveillance and to explore the association of this procedure with PSA levels and cancer progression rates.
To investigate the relationship between MRI evidence of prostatitis with clinical symptomatology. Non-malignant abnormalities in peripheral zone are common in prostate mpMRI. These findings are sometimes reported as “prostatitis” or “inflammation” and lead to patient anxiety and urologic referral.
Demographic and Socioeconomic Factors Associated with Urinary Stone Disease Management in a Large Urban US Population
To determine the influence of socioeconomic parameters on urinary stone surgeries.
Patterns of recurrence, detection rates, and impact of 18-F Fluciclovine PET/CT on the management of men with recurrent prostate cancer
To evaluate the characteristics of FACBC PET/CT in detecting recurrent prostate cancer after radiation or prostatectomy. The secondary aim was to determine the impact of FACBC PET/CT on radiation treatment recommendations in men with biochemical recurrence post-prostatectomy.
Guideline-Discordant Preoperative Gentamicin Dosing and the Risk of Gentamicin Associated Nephrotoxicity in Urologic Surgery
To determine the rate of and predictors for guideline-discordant preoperative gentamicin dosing in urologic surgery and to assess the risk of nephrotoxicity in patients who receive the recommended high-dose prophylaxis.
To determine the effect of prostate biopsy on erectile function we conducted a systematic review and meta-analysis up to August 2020. Mean difference of International Index of Erectile Function-5 (IIEF5) compared to baseline scores were pooled at one, three and six-months using a random effect model. Of 47 full text articles identified, 7 were included in the meta-analysis. A significant reduction in mean IIEF5 of 4.61 (0.32-8.91, p=0.04) was found at one-month post biopsy. This resolved with non-significant differences at three- and six-months post procedure.
To characterize kidney function in patients with exstrophy-epispadias complex (EEC) at time of presentation for adult urologic care.
Testosterone and Estrogen Repletion in a Hypogonadal Environment Improves Post-operative Angiogenesis
To determine the effects of perioperative hormone supplementation on postoperative periurethral angiogenesis in the setting of hypogonadism, we analyzed the urethral tissue of castrated Sprague Dawley rats supplemented with testosterone or estrogen who underwent a urethral surgery and compared it to those that did not.
Protective Effects of Metformin against Biochemical Failure Following Radical Prostatectomy or Radiation Therapy in Localized Prostate Cancer
To assess the impact of metformin on biochemical failure (BF) in localized prostate cancers (PC) treated with radical prostatectomy (RP) or radiation therapy (RT).