Urology News Feeds
Does a Positive Surgical Margin after Nephron Sparing Surgery Affect Oncological Outcome in Renal Cell Carcinoma? A Systematic Review and Meta-Analysis
We systematically evaluated the impact of positive surgical margins (PSM) on oncological outcomes after partial nephrectomy for renal cell carcinoma. Forty two studies comprising 101,153 subjects were included and 5 distinct meta-analyses were performed. PSM was associated with increased risk of local recurrence (HR 6.11 - high certainty), metastasis (HR 3.29 - moderate certainty), overall relapse (HR 2.25 - high certainty), overall mortality (HR 1.30 - moderate certainty), and may be associated with increased cancer-specific mortality (HR 1.91 - low certainty).
Outcomes of Active Surveillance for Men with Intermediate Risk Prostate Cancer, A Population-Based Analysis
To assesses if active surveillance (AS) is an appropriate treatment modality for patients with intermediate risk (IR) prostate cancer (PCa) utilizing population-level data to compare the survival outcomes of men with low risk (LR) and IR PCa initially treated with AS, watchful waiting (WW) or active treatment (AT).
Prostate Cancer Incidence and Mortality Following a Negative Biopsy in a Population Undergoing PSA Screening
Transrectal ultrasound guided biopsy for diagnostic workup for prostate cancer (PCa) has a substantial false negative rate. We sought to estimate PCa incidence and mortality following negative biopsy in a cohort of men undergoing prostate cancer screening.
To demonstrate the key steps to perform robot-assisted magnetic resonance imaging-ultrasound fusion transperineal prostate biopsy.
Epidural blockade for alternative management of priapism: A case report of child with T-cell acute lymphoblastic leukemia
Priapism is a clinical condition that rarely presents with leukemia in childhood. Management of priapism treatment can become more complex and difficult when accompanied by acute leukemia. We presented a 16 years old child with t-cell acute lymphoblastic leukemia (ALL) who developed priapism. Due to the failure of conservative methods and intracavernosal drainage, we performed epidural blockade which has limited data reported with successful results in the literature before shunt surgery.
Hydronephrosis and Hydroureter Improvement Rates in Robotic-Assisted Laparoscopic Uretero-Ureterostomies: Does Anastomotic Site Matter?
To compare improvement/change of hydronephrosis and hydroureter in patients with complete ureteral duplications that underwent upper and lower robotic-assisted laparoscopic uretero-ureterostomies. The hypothesis being that improvement of hydronephrosis and hydroureter between the two groups was similar.
To verify the effect of Pilates training combined with biofeedback training, Kegel training combined with biofeedback training, and Kegel training alone on post-prostatectomy incontinence in male patients.
Sexual function (SF) may be profoundly altered by cancer treatment with reported rates of sexual dysfunction ranging from 6-96% across all cancer types.1 Among women, sexual dysfunction was reported at >65% across all cancer types with the highest prevalence in those with gynecologic disease.2 Sexual dysfunction negatively impacts quality of life (QoL) and intimate partner relationships, ultimately contributing to higher rates of morbidity and mortality among cancer survivors.3,4
Determining Perioperative Practice Patterns in Urethroplasty: A Survey of Genitourinary Reconstructive Surgeons
Objectives: To better delineate perioperative urethroplasty practice patterns among reconstructive urologists given that management strategies in reconstructive urology have generally been poorly described.Methods: An online survey examining perioperative management of anterior urethroplasty patients was administered to Society of Genitourinary Reconstructive Surgeons (GURS) members between August-October 2019. Questions pertained to tissue transfer, pharmacologic prophylaxis, catheter use, follow-up, and post-operative care.
Sickle cell disease (SCD) is an inherited medical condition where sickled red blood cells cause vaso-occlusive crises. One major complication of SCD is priapism, defined as an erection of the penis lasting over four hours beyond sexual stimulation or orgasm. SCD priapism is caused by sickled erythrocytes obstructing venous outflow and can lead to permanent erectile dysfunction. This article reviews the pathology, physiology, and management of SCD priapism, including potential novel therapeutic agents.
To investigate whether penile pathologies are presented diversely in urologic textbooks and identify areas where more diverse presentation is warranted.
To evaluate Medicaid insurance access disparities for urologic care at urgent care centers (UCCs) in the United States.
To address healthcare inequities, diversifying the physician workforce is an important step and improved efforts to recruit Underrepresented in Medicine (URiM) students is vital. We aim to examine the current state of minority recruitment and provide solutions to increase diversity in urology residency training.
A 67-year-old female is referred from gynecology due to irritative voiding symptoms, urethral pain, and a vaginal bulge. On exam, a friable lesion can be seen protruding from the urethral meatus, and can be palpated transvaginally to extend proximal to the bladder neck. Transvaginal biopsy demonstrates clear cell adenocarcinoma (CCA).
To measure burnout and career choice regret from the American Urological Association Census, a national sample of urology residents, and to identify unmet needs for well-being.
Detection of clinically significant prostate cancer by systematic TRUS-biopsies in a population-based setting over a 20 year period
To assess the performance of systematic TRUS-biopsies in a population-based setting to detect clinically significant PCa (csPCa) in combination with age, clinical tumor category (cT), and prostate-specific antigen (PSA) in men referred for the first biopsy.
Direct Oral Anticoagulants for Venous Thromboembolism Prophylaxis Following Robot-Assisted Radical Cystectomy: A Retrospective Feasibility Study at a Single Academic Medical Center
To evaluate the use of direct oral anticoagulants following radical cystectomy for venous thromboembolism prophylaxis. We compared the experience of those who received venous thromboembolism prophylaxis following a robot-assisted radical cystectomy with either a direct oral anticoagulant or enoxaparin.
Dorsal Onlay Buccal Mucosal Graft Urethroplasty In Post Radiation Female Urethral Stricture- A Technical Appraisal with Outcomes
Female urethral stricture following radiation has been reported sparsely in the literature with just a handful of case reports. Radiation to the pelvis affects the genitourinary tracts and afflicts damage by causing periurethral fibrosis, necrosis, and subsequent tissue contraction, posing as a hurdle to the reconstructive surgeon. We studied the technique and outcomes of Dorsal Onlay Buccal mucosal graft (BMG) urethroplasty in patients of radiation-induced female urethral stricture disease (FUSD).
Female urethral stricture is a rare, but often underrecognized, cause of voiding dysfunction in females.1 Vaginal free graft urethroplasty has been shown to have good efficacy and durability in treating urethral stricture, though accessible descriptions of technique are not widely available.1,2 Accordingly, we set out to describe and demonstrate our technique for vaginal mucosal free graft dorsal onlay urethroplasty.
Prognostic role of FGFR alterations and FGFR mRNA expression in metastatic urothelial cancer undergoing checkpoint inhibitor therapy
To examine the disease-specific survival(DSS) after checkpoint inhibitor(CPI) therapy based on FGFR alterations and FGFR mRNA expression levels in patients with metastatic urothelial cancer(mUCa) within a multi-center cohort.