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Access and Representation: A Narrative Review of the Disparities in Access to Clinical Trials and Precision Oncology in Black men with Prostate Cancer
Objective:To provide commentary on the disparities in access to clinical trials and precision oncology specific to Black men with Prostate Cancer (PCa) in the United States and lend a general framework to aid in closing these gaps.Materials and Methods: The ideas, commentaries and data presented in this narrative review were synthesized by utilizing qualitative and quantitative studies, reviews, and randomized control trials performed between 2010 and 2021. We searched PubMed using the key words “Medicaid”, “Medicare”, “clinical trials”, “African Americans”, “Black”, “underrepresentation”, “access”, “Prostate Cancer”, “minority recruitment”, “racial disparities”, “disparity”, “genomics”, “biomarkers”, “diagnostic” “prognostic”, “validation”, “precision medicine”, and “precision oncology” to identify important themes, trends and data described in the current review.
Longitudinal Outcomes from Conservative Management of Cervical Cancer Associated Ureteral Obstruction
: To identify predictors of hydronephrosis (HN) resolution and HN treatment failure. HN is a common comorbid condition with cervical cancer (CCa). Treatments for CCa continue to improve and long-term management strategies of HN are becoming increasingly necessary.
To investigate the relationship between metabolic syndrome (MetS) and lower urinary tract symptoms (LUTS) with functional and anatomic changes of the lower urinary tract with MRI.
Bladder neck angle associated with lower urinary tract symptoms and urinary flow rate in patients with benign prostatic hyperplasia
: To evaluate the effect of the funnel-shaped structure of the bladder neck in patients with benign prostatic hyperplasia (BPH), we investigated the correlation of the bladder neck angle (BNA) with the urinary flow rate and lower urinary tract symptoms (LUTS).
To identify the current formats of standardized letters of recommendation (SLORs) and evaluate their characteristics, the distribution of applicants’ ratings, correlation between SLOR domain ratings and conventional application metrics, and potential biases.
To describe and assess the outcomes of dorsal onlay oral mucosa graft urethroplasty for female urethral stricture.
Clinical Outcomes of Robotic Assisted Partial Nephrectomy for Pathologic T3a Renal Masses with Venous Tumor Thrombus
To evaluate the safety, efficacy, and early oncologic outcomes of pT3a renal cell carcinoma (RCC) with venous involvement treated with robotic partial nephrectomy (RPN), given that experience and outcomes in this group is limited.
To identify the currently utilised techniques of anterior urethroplasty described in literature for treatment of urethral strictures, assess the effectiveness of the identified techniques based on re-stricture and complication rates, evaluate, and suggest treatment options based on current evidence for urethral strictures at different locations and of different lengths.
To determine whether health-conscious men are more likely to be concerned about infertility and self-initiate semen analysis at a laboratory/clinic or through a direct-to-consumer at-home product without a health care provider recommendation.
Effects of cells self-aggregation in the treatment of neurogenic erectile dysfunction with traditional single cell suspension of adipose-derived stem cells
: To clarify the effects of cellular self-aggregation of adipose-derived stem cells (ADSCs) on erectile function (EF).
Noncancerous Genitourinary Conditions as a Public Health Priority: Conceptualizing the Hidden Burden
To provide a conceptual framework to guide investigations into burdens of noncancerous genitourinary conditions (NCGUCs), which are extensive and poorly understood.
Endoscopic Management of Low-Grade Upper Tract Urothelial Carcinoma: Characterizing the Long-term Burden of Care in Comparison to Radical Nephroureterectomy
To compare procedure burden, oncologic, surgical and renal-function outcomes between patients with low-grade upper urothelial cancer (UTUC) who were referred for either radical management (RM) or kidney-sparing endoscopic management (EM).
A 39-year-old young woman was referred to the cardiology department because of 'dizziness for 1 week'. She had a history of hypertension for 3 years, which was treated with irbesartan, but had poor blood pressure control for 1 week. The laboratory examination revealed an elevated renin level of 1000uIU/ml. An enhanced computed tomography (CT) scan of the abdomen demonstrated a soft-tissue mass in the upper pole of the left kidney. The patient was admitted for further evaluation. Admission labs were notable for a serum potassium of 2.93mmol/L.
Underrepresentation of Racial and Ethnic Diversity in Research Informing the AUA/SUFU Stress Urinary Incontinence Guideline
To characterize the racial/ethnic representation in the studies used in the American Urological Association (AUA)/ Society of Urodynamics, Female Pelvic Medicine & Urogenital Reconstruction (SUFU) stress urinary incontinence (SUI) guideline.
Social determinants of kidney stone disease: the impact of race, income and access on urolithiasis treatment and outcomes
The medical and surgical management of kidney stones is one of the most common functions of the urologist. Management choices are often nuanced, involving the decision to embark on one surgical plan among several options. As the wider medical community critically evaluates the care we provide to an increasingly diverse population, it will be important to examine patient outcomes with a particular focus on ensuring equitable care. This review examines the influence of social parameters on the care of kidney stone patients.
Formal Mentorship as an Opportunity to Expand the Urology Pipeline: UnderRepresented Trainees Entering Residency (UReTER) Program Evaluation 2020-2021
To rank percentages of underrepresented residents in surgical subspecialties and understand the experience of mentees and mentors who participated in the inaugural University of California, San Francisco Urology UnderRepresented Trainees Entering Residency (UReTER) Mentorship Program for Black, Indigenous, and/or LatinX medical students applying into urology.
A statewide quality improvement collaborative's adherence to the 2017 AUA guidelines regarding initial evaluation of patients with cT1 renal masses
Objectives: To evaluate MUSIC-KIDNEY's adherence to the AUA guidelines regarding initial evaluation of patient's with clinical T1 (cT1) renal masses.Methods: We reviewed MUSIC-KIDNEY registry data for patients with newly diagnosed cT1 renal masses to assess for adherence with the 2017 AUA guideline statements regarding recommendations to obtain 1) CMP, 2) CBC 3) UA, 4) abdominal cross-sectional imaging and 5) chest imaging. An evaluation consisting of all 5 guideline measures was considered “complete compliance”.
To determine the durability of ureteroneocystostomy as well as pre- or post-operative factors that may be associated with failure to provide appropriate renal drainage.
To evaluate management patterns, measure familiarity with the new guidelines, and gauge the level of education and confidence in treating rUTIs according to recent guidelines, specifically in the context of trainee education. Recurrent urinary tract infections (rUTI) are a common urologic complaint and a heavy burden on the healthcare system. Until recently, the AUA did not have a guideline on the management of rUTIs.
Institutional Opioid Prescription Guidelines are Effective in Reducing Post-operative Prescriptions Following Urologic Surgery: Results from the American Urologic Association 2018 Census
To assess provider and practice characteristics that drive opioid prescription behavior using the American Urological Association census data.